Figure 3 - full size

 

Figure 3.
FIGURE 3. Docking model of the N-terminal domain dimer structure of STAT4 onto the dimeric STAT5a core fragment assuming coincidence of their dyads. A, side view of the ensemble. An arrow indicates the dyad. Dashed lines symbolize the missing residues between the C termini of the N-terminal domains and the N termini of the core domains. The color coding for the STAT5a dimer is identical to the one used in Fig. 1A, and the N-terminal domain dimer is colored in cyan. B, electrostatic potential representations of matched surfaces of the docking partners. The common 2-fold axis is indicated by an X, and the complementary surfaces are encircled.

The above figure is reprinted by permission from the ASBMB: J Biol Chem (2005, 280, 40782-40787) copyright 2005.