Figure 3 - full size

 

Figure 3.
Figure 3. Diagrams of the hydrogen bonding networks in the active site of (a) subunit A and (b) subunit B with the Grb2 SH2 domain represented in cartoon, ligand-binding residues in bonds with grey carbon atoms, and ligands in ball-and-stick with green carbon atoms. Hydrogen bonds are in cyan broken lines and intramolecular bonds in red. Selected atoms of S1s are labeled in red.

The above figure is reprinted by permission from Elsevier: J Mol Biol (2005, 353, 104-115) copyright 2005.