Figure 3 - full size

 

Figure 3.
FIGURE 3. A comparison of human galactokinase versus GalNAc kinase. The human forms of galactokinase and GalNAc kinase differ in three specific regions labeled A, B, and C and indicated by the blue ribbons in a. A superposition of the sugar binding regions for these enzymes is given in b. The yellow bonds correspond to GalNAc kinase, with the sugar ligand depicted in aquamarine. The white bonds correspond to galactokinase, with the sugar ligand highlighted in magenta. The red and black labels correspond to residues in galactokinase and GalNAc kinase, respectively. Coordinates for the human galactokinase were from this laboratory (Protein Data Bank accession number 1WUU [PDB] ).

The above figure is reprinted by permission from the ASBMB: J Biol Chem (2005, 280, 32784-32791) copyright 2005.