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Figure 3.
Figure 3
The iodide ions in the Fab15A9-PPL-L-Ala structure. A [sigma] [A]-weighted F[obs] -
F[calc] electron-density map omitting the iodide ions is contoured at the level of 2
[sigma] and superimposed on the active-site structures. (a) Stereoview of the
non-occupied active site of the Fab15A9-PPL-L-Ala complex. One iodide ion takes the place
of the phosphate group in one molecule of the asymmetric unit. (b) The conformation of
CDRH3 is stabilized by an iodide ion. In each molecule of the asymmetric unit, one iodide
ion makes four 3.0-3.8 Å interactions with the NH groups of His97 and His99, TrpH100e N
[epsilon] 1 and AsnH100a N [delta] 2. (c) One iodide ion interacts with the two
molecules of the asymmetric unit. At the corresponding position in the other molecule, one
iodide ion is involved in a crystallographic contact.
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