Figure 3 - full size

 

Figure 3.
Fig. 3. Sequence diversity in GATA-binding FOG ZnFs. (A) The GATA-FOG structure showing the position of A225[dFOG] (Left), and the likely position of the valine side chain that replaces A225 in a complex formed between NF and mFOG-F6 (Right). (B) Position of the S218 side chain and the two nearby glutamates from NF (Left). (Right) The likely position of the arginine side chain that would replace S218 in a NF/mFOG-F1 complex.