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Figure 3.
Figure 3 Recognition of 2-5A by ANK. (A) Stereodiagram showing
the mode of 2-5A binding to ANK. The carbon atoms of ANK are
colored as in Figure 1, and those of the bound 2-5A molecule are
shown in white. Possible hydrogen bonds or salt bridges are
indicated by dashed lines, and distances (in Å) are given. The
refined model is superimposed on the weighted 2|F[o]| -|F[c]|
map (1.5  ,
yellow) and the |F[o]| -|F[c]| omit map of 2-5A (4.5 ,
orange), calculated at 1.8 Å resolution. Bound water molecules
are shown as spheres (cyan). (B, C) Recognition of the first and
third AMP moieties of 2-5A by repeats 4 and 2, respectively, of
ANK.
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