Figure 3 - full size

 

Figure 3.
Figure 3. Ribosomal binding site for RACK1. (a) View of the anchoring region of RACK1 (red) showing interactions with the 18S rRNA helices 39 and 40. (b) View of RACK1 and protein neighbors, rpS3 (S3p), rpS5 (S7p), rpS16 (S9p) and rpS20 (S10p) from the 40S subunit head region (corresponding ribosomal proteins in E. coli are indicated in parentheses). Thumbnails to the right of each panel represent 40S subunit structure in the corresponding views to aid orientation. Atomic coordinates for small subunit proteins and 18S rRNA were taken from PDB entry 1S1H23, and all representations were made using Ribbons44. Landmarks of the 40S subunit: bk, beak; pt, platform.

The above figure is reprinted by permission from Macmillan Publishers Ltd: Nat Struct Mol Biol (2004, 11, 957-962) copyright 2004.