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Figure 3.
Figure 3. Interactions between the Third Phospho-20 aa
Repeat of APC and β-Catenin(A) Stereo 2Fo - Fc simulated
annealed omit map of the phosphorylated third 20 aa repeat of
APC (labeled in red) bound to β-catenin. The map is contoured
at 1σ.(B) Electrostatic surface of β-catenin (armadillo
repeats 1-5) bound to the phosphorylated third 20 aa repeat and
its C-terminal residues. APC and β-catenin are colored as in
Figure 2A.(C) Critical contacts in the interface of the
phospho-20 aa repeat of APC bound to the β-catenin groove
formed by armadillo repeats 1-5. APC and β-catenin are colored
as in Figure 2C.
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