Figure 3.
FIG. 3. Stereo view of AA bound within the active site of
V349A/W387F oPGHS-1. The simulated annealing omit map F[o] -
F[c] density contoured at 4.0 is shown in green.
Carbon atoms of AA, which were originally built into the
electron density, are shown in pink (atoms C-1-C-12). Carbon
atoms of AA obtained from simulated annealing are shown in blue.
Side chains of various amino acids that line the COX active site
and contact the substrate are shown in a color scheme where
carbons are gray, oxygens are red, nitrogens are dark blue, and
sulfur is yellow. All of the figures were created using the
program SETOR (22).
The above figure is reprinted
by permission from the ASBMB:
J Biol Chem
(2004,
279,
42929-42935)
copyright 2004.
is shown in green.
Carbon atoms of AA, which were originally built into the
electron density, are shown in pink (atoms C-1-C-12). Carbon
atoms of AA obtained from simulated annealing are shown in blue.
Side chains of various amino acids that line the COX active site
and contact the substrate are shown in a color scheme where
carbons are gray, oxygens are red, nitrogens are dark blue, and
sulfur is yellow. All of the figures were created using the
program SETOR (22).