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Figure 3.
Figure 3 PYM binds Mago -Y14 with extensive interactions. (A)
Schematic view of the PYM -Mago -Y14 complex (left panel) and
schematic diagram highlighting the key residues involved in the
interaction (right panel). Positively charged residues of PYM
interact with negatively charged residues of Mago helices  1
and 2.
In addition, PYM interacts with the  2
- 3
loop of Y14 by means of hydrophobic contacts. Colours are as in
Fig 2. Hydrogen bonds are shown with dotted lines. (B) Stereo
representation of the structure and of the interacting residues
in a similar orientation as in Figs 2A,3A.
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