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Figure 3.
Figure 3. (a) Stereo view of cavities in Ag85C2 (gray)
versus MPT51 (cyan) superimposed with the ribbon diagram of
MPT51. The trehalose molecule of the structure of Ag85B[20.] is
shown as a guide for the eye. (b) Stereo view of the
superimposition of the structures of the effector domain of E.
coli TreR[37.] (blue) and of the S. typhimurium
glucose/galactose receptor[38.] (green) with MPT51 (gray). The
trehalose-6-phosphate ligand of TreR (red rods) and the
trehalose molecule (yellow) of the Ag85B structure are shown.
(c) and (d) Surface diagrams of (c) MPT51 and (d) Ag85B colored
according to sequence conservation (red=identity). The surface
area corresponding to the fibronectin-binding loop is marked in
green. The Figure was prepared using (a) SURFNET, [28.] (a) and
(b) RIBBONS [53.] and (c) GRASP. [54.]
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