Figure 3.
FIG. 3. Quantitative measurement of the PAK-GBD interaction
with Rac1 (A) and Rac1b (B). Dissociation of mantGppNHp from
Rac1b was inhibited by increasing concentration of the PAK-GBD
(2-50 µM). The observed rate constants were plotted
against the concentration of the PAK-GBD to obtain equilibrium
dissociation constants of 0.49 µM for Rac1 and 3.55
µM for Rac1b.
The above figure is reprinted
by permission from the ASBMB:
J Biol Chem
(2004,
279,
4743-4749)
copyright 2004.
