Figure 3.
FIG. 3. Structure of active c-Kit kinase. The C ribbon
illustrates the two-domain kinase fold and key structural
elements, including the C-helix, phosphate-binding P-loop,
adenine-recognition hinge loop, and kinase activation A-loop.
The positions of the ADP, metal ion, and substrate peptide are
also shown.
The above figure is reprinted
by permission from the ASBMB:
J Biol Chem
(2003,
278,
31461-31464)
copyright 2003.
ribbon
illustrates the two-domain kinase fold and key structural
elements, including the C-helix, phosphate-binding P-loop,
adenine-recognition hinge loop, and kinase activation A-loop.
The positions of the ADP, metal ion, and substrate peptide are
also shown.