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Figure 3.
Figure 3: Surface features of the Sec23/24 complex a, Molecular
surface coloured according to electrostatic potential50:
negative potential is red and positive potential blue. Sar1
is drawn as a backbone tube in magenta. The three views are
successive 90° rotations around a vertical axis. In the left
image, the membrane-proximal surface faces forwards. b, Surface
of Sec23/24 coloured according to sequence conservation of the
underlying residues in an alignment of Sec23 sequences from six
organisms (human Sec23A, Drosophila melanogaster, Neurospora
crassa, Schizosaccharomyces pombe, Arabidopsis thaliana and
Saccharomyces cerevisiae) and Sec24 sequences from four
organisms (human Sec24A, S. pombe, A. thaliana and S.
cerevisiae). Labels I, II and III indicate three highly
conserved patches (see text for details). The orientations are
the same as in a, with Sar1 omitted.
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