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Figure 3.
Fig 3. (A) Ribbon diagram of subtilisin/CI2 complex
structure. Subtilisin is shown in red, the N-terminal section of
CI2 is shown in dark blue, and the C-terminal section of CI2 is
shown in light blue. The reactive site peptide bond is at the
junction of the dark and light blue segments. (B) Closer view of
reactive site loop. CI2 side chains (labeled in white) and
hydrogen bonds (yellow dotted lines) proposed to stabilize the
positioning of the light blue (leaving group) side of the loop
after acyl-enzyme formation (see text) are shown in detail. The
serine, histidine, and aspartate of the subtilisin catalytic
triad are also shown (labeled in yellow).
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