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Figure 3.
Fig. 3. Estradiol binds to human SHBG in an opposite
orientation when compared with 3 ,17 Adiol. A,
stereo image of the human SHBG steroid-binding site occupied by
estradiol. B, superposition of the steroid-binding site in the 3
,17 Adiol (in
blue) and estradiol (in yellow) complexes, illustrating the
differences in steroid orientation and coordination. Images were
prepared with Molscript (34) and Raster3d (35).
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