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Figure 3.
Fig. 3. (A) Two clipped views of the active site showing
the inhibitor (as cpk model) fitting the cavity are shown. The
molecular surface of the protein is represented as a white mesh.
Bromine atoms are in red, carbon atoms in green, and nitrogen
atoms in blue. (B) Position of TBB with respect to that of ATP
(cyan) and emodin (green) in the catalytic site is shown from
different points of view. Inhibitor rings lay practically in the
same plane of the purine moiety of the natural cosubstrates
(bottom).
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