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Figure 3.
Figure 3. Model of the E2-Ub Thiolester IntermediateThe
model was determined by Monte Carlo docking as described in
Experimental Procedures. The model shows (a) side and (b) end
orientation views of helix a2 in the E2 molecule. Residues are
indicated on both E2 and Ub to indicate important side
chain-side chain interactions that arise at the protein-protein
interface, as described in the text. In both figures, the
thiol-forming C88 residue in E2 is a shown as a yellow
ball-and-stick representation near the (a) center and (b) top of
the complex
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