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Figure 3.
Figure 3: Surface representations of G115. a, The surface of
G115 is coloured by CDR loops (CDR1, blue; CDR2, green; HV4,
pink; and CDR3, red). b, 3-formyl-1-butyl-pyrophosphate is shown
as a drawing and as a space-filling model (at the same scale as
G115 in a and c). c, The surface potential of G115 is
colour-coded from red (-10 kT) to blue (+10 kT). The top of the
molecule, containing the CDR loops, is facing the viewer. The
cleft between the two CDR3 loops contains positively charged
patches (blue), which line the phosphoantigen-binding site. d,
Enlarged view of the cleft shows the location of charged
(negative in red; positive in blue), hydrophobic (yellow) and
polar (green) residues.
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