Figure 3 - full size

 

Figure 3.
Figure 3. Stereo figures of the complementarity determining regions (CDRs) and the fourth hypervariable region (HV4). (a) CDR1 of Va85.33 (carbon atoms are shown in gray) superimposed on the CDR1 of A6 (carbon atoms are shown in cyan). (b) CDR2 of Va85.33 (carbon atoms are shown in gray) superimposed on the CDR1 of A6 (carbon atoms are shown in cyan). (c) The backbone of the Va85.33-CDR3 regions of all four molecules in the asymmetric unit (colored in red, green, blue and yellow) superimposed on the CDR3 regions of A6, TCR, B.4.2.3, KB5, N15-C20, B7, BM3.3, HA1.7, and 1934.4 (colored in gray). (d) The backbone of the Va85.33-HV4 regions of all four molecules in the asymmetric unit (colored in red, green, blue and yellow) superimposed on the HV4 regions of A6, TCR, B.4.2.3, KB5, N15, B7, D10, BM3.3, HA1.7, and 1934.4 (colored in gray).

The above figure is reprinted by permission from Elsevier: J Mol Biol (2001, 310, 689-698) copyright 2001.