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Figure 3.
Figure 3: Cryo-EM maps of the microtubules decorated by the
KIF1A. a, A 22 Å resolution map of the KIF1A -AMPPNP
-microtubule complex15. The motor core (yellow) and its long
axis (red line) are shown. The microtubules are shown with their
plus end up in this and following figures. b, Docking of the
ATP-like KIF1A crystal structure into 15 Å resolution cryo-EM
map of the microtubule (grey) complexed with the KIF1A (yellow)
in the presence of AMPPNP15. The C-terminal region of tubulin
(E-hook) is shown in yellow. c, A 22 Å resolution map of the
KIF1A -ADP -microtubule complex. The long axis of the motor is
indicated by a red line. For comparison, its orientation in the
ATP-like state is indicated by the orange grid and pink line. d,
Docking of the ADP-bound KIF1A crystal structure into
electron-microscopy-derived 22 Å resolution map. The colours are
the same as in b.
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