Figure 3 - full size

 

Figure 3.
Figure 3: Representation of Tiam1/Rac1 interface contacts. The model of Rac1 on the left in green (with switch regions in red) has been rotated 180° about the vertical axis from its relative orientation with respect to the DH domain (on right in yellow) to display the two interface surfaces. Residues in black type lose >10 Å2 of accessible surface area on complex formation. Associated intermolecular contacts are listed below, colour coded by interaction type (red, van der Waal's; green, hydrogen bonds; blue, ionic) and starred if non-ionic but involving side-chain atoms. Figure was made using Ribbons42.

The above figure is reprinted by permission from Macmillan Publishers Ltd: Nature (2000, 408, 682-688) copyright 2000.