Figure 3.
Fig. 3. Schematic diagram showing the intermolecular
interactions between S-1153 and the surrounding residues of
HIV-1 RT. The pink spheres represent water molecules in contact
with the inhibitor. Residues that contact the NNRTI with a
minimum interatomic distance of 3.6Å are
shown in green, whereas other residues lining the binding pocket
are shown in blue. The individual distances between the NNRTI
and the protein atoms are shown as dashed lines (distances less
than or equal to 3.3 Å are in pink; distances between 3.3
and 3.6 Å are in light blue; hydrogen bonds are shown
together with distances in black).
The above figure is reprinted
by permission from the ASBMB:
J Biol Chem
(2000,
275,
14316-14320)
copyright 2000.
3.6Å are
shown in green, whereas other residues lining the binding pocket
are shown in blue. The individual distances between the NNRTI
and the protein atoms are shown as dashed lines (distances less
than or equal to 3.3 Å are in pink; distances between 3.3
and 3.6 Å are in light blue; hydrogen bonds are shown
together with distances in black).