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Figure 3.
Fig. 3. Superposition of the m-calpain catalytic domain
and papain. The papain-like part of the catalytic domain (gold,
dIIa) and the barrel-like subdomain dIIb (red) are superimposed
with papain (18) (blue) after optimal fit of the left-side
papain half to the helical subdomain dIIa. The active site
residues Cys105L, His262L, and Asn286L, and Pro287L, Trp288L,
and Trp106L are shown in full structure. This "standard view" of
papain-like cysteine proteinases (18) is obtained from Fig. 1 by
a 90° rotation around a horizontal axis. The figure was made
with SETOR (34).
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