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Figure 3.
Figure 3. Superpositon of mutant structures with the wt crystal structure in the environment of the mutation site.
(a) Structure of A334I with the C
a
-trace in green and side-chains in magenta, and with the 2jF0
j - jF
C
j
electron den-
sity of residues 334 and 335 contoured at 1.5 s level in blue. The superposition of the wt backbone is shown in yel-
low with red side-chains. Note the bulging out of the backbone and the difference of Q335 in the mutant structure.
The structure of A334V is very similar to the structure of A334I shown here. (b) Superposition of wt (blue), V331A
(yellow), and V331G (red). Only residues near the mutation site are shown. The Figures were made using FRODO
(Jones et al., 1978) and MOLMOL (Koradi et al., 1996), respectively.
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