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Figure 3.
Figure 3. The overall fold of NAP. (a) Stereoview of the
structure of NAP from Desulfovibrio desulfuricans ATCC 27774
with the different domains coloured: domain I (residues 4–61,
464–492 and 517–561) in red; domain II (residues 62–135,
347–463 and 493–516) in green; domain III (residues
136–346) in yellow; and domain IV (residues 562–723) in
blue. The funnel-like cavity, which provides access to the
molybdenum catalytic site, can be seen on the upper part of the
molecule between domains II and III. (b) Stereoview Cα trace
of NAP for domains I and III with residues labelled. (c)
Stereoview Cα trace of NAP for domains II and IV with residues
labelled. The MGD cofactors and the [4Fe–4S] cluster are shown
in ball-and-stick representation. (Figures were prepared with
the programs MOLSCRIPT [75] and Raster-3D [76].)
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