Figure 3.
Figure 3 The PPAT hexamer. (A) Electrostatic surface potential
(using the program GRASP; Nicholls et al., 1991) of the PPAT
hexamer along the triad (red, negative; blue, positive; white,
uncharged). The diameter along the 3-fold axis is 75
Å, with a channel across the entire hexamer with a
diameter of at least 10 Å. The substrates and products
must enter through this cavity to bind to the active site of the
protein. Space-filling representations (using the program
RASTER3D; Bacon and Anderson, 1988; Merritt and Murphy, 1994)
looking down (B) the triad and (C) the dyad. Each of the six
subunits is coloured differently.
The above figure is reprinted
from an Open Access publication published by Macmillan Publishers Ltd:
EMBO J
(1999,
18,
2021-2030)
copyright 1999.
75
Å, with a channel across the entire hexamer with a
diameter of at least 10 Å. The substrates and products
must enter through this cavity to bind to the active site of the
protein. Space-filling representations (using the program
RASTER3D; Bacon and Anderson, 1988; Merritt and Murphy, 1994)
looking down (B) the triad and (C) the dyad. Each of the six
subunits is coloured differently.