Figure 2 - full size

 

Figure 2.
Figure 2 Stereo views. a, erythropoietin-(EPObp)[2]. b, (EMP1-EBP)[2]. c, hGH-(hGHbp)[2]. All the receptors are coloured blue, with their ligands in red. The intermolecular contacts (<4.5 Å) involving receptor amino acids are shown in yellow; ligand amino acids with the receptor on the right-hand side (site 1 for erythropoietin and hGH) are shown in green; and ligand amino acids with the receptor on the left-hand side (site 2 for erythropoietin and hGH) are shown in white. Receptor orientations are also represented schematically at the right, with the horizontal membrane plane shown in grey and the corresponding vertical plane drawn in a chequered pattern.

The above figure is reprinted by permission from Macmillan Publishers Ltd: Nature (1998, 395, 511-516) copyright 1998.