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Figure 2.
Figure 2. Ribbon Rendering of Flt-1[D2], in Two Views
Related by a Rotation of Approximately 90° about the
Vertical AxisThe termini and the secondary structure elements as
defined by the program Procheck ([26]) are labeled; β strands
are rendered as green arrows, the helical turn as a green
ribbon, and the loop regions as gray tubes. The disulfide bond
is shown in ball-and-stick rendering, with sulfur atoms colored
yellow. The two potential N-linked glycosylation sites at
Asn-164 and Asn-196 are colored blue. The VEGF binding site is
located on the “bottom” end of the five-stranded sheet;
residues in contact with VEGF in the complex are colored red. A
segment near the N terminus, which forms strand βa in members
of the I set of the immunoglobulin superfamily, bulges away from
the core of the domain. This figure was created using the
program MOLMOL ( [24]).
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