Figure 2.
Fig. 2. Stereo iew of 5-amidinoindole4-benzylpiperidine bond to the active site of human a-thrombin. heomittedelectrondensity
mapcorresponding to theinhibitor,whichwasued to position LY178550 intheactive site, is shown. The mapiscontouredat 1.0
level,with (2F, - a;) oefficientsat a resoluion of 2.07 A.
The above figure is reprinted
from an Open Access publication published by the Protein Society:
Protein Sci
(1997,
6,
1412-1417)
copyright 1997.