Figure 2 - full size

 

Figure 2.
Fig. 2. Stereo iew of 5-amidinoindole4-benzylpiperidine bond to the active site of human a-thrombin. heomittedelectrondensity mapcorresponding to theinhibitor,whichwasued to position LY178550 intheactive site, is shown. The mapiscontouredat 1.0 level,with (2F, - a;) oefficientsat a resoluion of 2.07 A.

The above figure is reprinted from an Open Access publication published by the Protein Society: Protein Sci (1997, 6, 1412-1417) copyright 1997.