Figure 4.
Fig. 4. Final (2F, - F, I omitelectrondensitymaps at the active of
cy-thrombincomplexedwith (A) BMS-186282 and (B) BMS-189D90 su-
perimposewiththefinalthree-dimensionalstructures of the inhibitors.
Electron densitymapswerecalculatedusingX-PLOR(Briinger,1989).
The above figure is reprinted
from an Open Access publication published by the Protein Society:
Protein Sci
(1996,
5,
221-228)
copyright 1996.