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Figure 3.
Figure 3. Stereo section of the final electron density map (blue) around the bound benzamidine molecule (center),
superimposed on the t-PA model. Standard view as in Figures 1 and 2. Of the protein structure, only the entrance frame
Trpc215 to Cysc220 (around the benzamidine), the catalytic triad Serc195, Hisc57 and Aspc102 (to the east), and Lysc143
and Tyrc151 (to the south) are displayed; the spherical density east of the benzamidine molecule, which partially hides
the active Ser195, represents the bound phosphate ion. Contouring is at 1.0s. Figure made with O (Jones et al., 1991).
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