Figure 2 - full size

 

Figure 2.
Figure 2. Schematic diagram showing the folding topology of the d(G-C-G-G-T3-G-C-G-G) quadruplex in Na + containing solution. The backbone tracing of individual hairpins is shown by thick lines and the chain directionality by thick arrows. Hydrogen bonding donor to acceptor directionalities around individual G·G·G·G tetrads are represented by arrows as are Watson-Crick G·C pairs within G·C·G·C tetrads. Syn guanine residues are shaded to distinguish them from anti guanine residues. The two distinct inter-strand narrow grooves are labelled N1 and N2 while the symmetric intra-strand wide grooves are labelled W.

The above figure is reprinted by permission from Elsevier: J Mol Biol (1995, 254, 638-656) copyright 1995.