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Figure 2.
PA26-proteasome binding studies. A–E, biosensorgrams
showing concentration-dependent binding of PA26 variants to the
S. cerevisiae proteasome and calculated average dissociation
constants (K[D]). Binding to an IgG control surface was
negligible (data not shown). RU, response units. F, kinetic plot
of k[a] versus k[d] where diagonals represent K[D], and values
for each PA26 variant are shown as spots. The K[D] standard
deviation is less than the size of the spots.
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