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Figure 2.
Fig. 2. Structures of the CS-35Fab CDRs. (a and b)
Space-filling representations of CDRs H1 (magenta), H2 (orange),
H3 (red), L1 (blue), L2 (cyan) and L3 (green) bound to compound
3 (yellow dots). (c) Sequences of the CS-35Fab CDRs, with
asterisks denoting residues forming direct or water-mediated
contacts with compound 3. Residue numbering follows the Kabat
convention, as implemented in Abnum.^23 For reference, the
normal sequential numbering of residues of CDR H2 and that of
residues of CDR H3 are shown as white numbers against a black
background below the Kabat numbering. The normal sequential
numbering of residues in CDR H1 and that of residues in the
light chain are identical with the Kabat numbering.
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