Figure 2 - full size

 

Figure 2.
Comparison of the solution structures of the Pin1 WW domain. (A) Superposition of 12 structures of the WT protein (36; PDB ID code 2kcf) (B) Superposition of 15 structures of variant C-4 (PDB ID code 2kbu). (C) Superposition of a low-energy structure from each of the ensembles in (A) and (B). The inset shows the structure of dipeptide replacement 4 in loop 1.