Figure 2 - full size

 

Figure 2.
Influence of the C-terminal truncation on the conformation of the inner helix bundle gate. (A) Cα superposition of the high-resolution truncated KcsA structure (1K4C; red ribbons) with FL KcsA (blue ribbons). Inset highlights the splaying out of the inner helix bundle gate between residues 110 and 115, resulting in a 15° outward tilting. (B) Radius profile (calculated with the program HOLE; ref. 29) of truncated (red) and FL KcsA (blue).