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Figure 2.
Fig. 2. NMR and crystal structures of Dbp5p proteins. (a) NMR
structure of CTD of ScDbp5p. α-helices and β-strands are
colored cyan and magenta, respectively. The extreme C-terminal
helix in CTD is shown in red. The first residue number of CTD is
296. (b) NMR structure of NTD of ScDbp5p. The color coding is
the same as that in (a) with the exception that the N-terminal
extension region is shown in green. (c) Overall structure of
SpDbp5p solved by X-ray chromatography. The color coding is the
same as that in (a). (d) Stereo view of superposition of SpDbp5p
and HuDbp5p-ADP at the NTD. SpDbp5p is colored yellow and
HuDbp5p-ADP is in gray, with its N-terminal region in magenta
and the bound ADP in stick model. (e) Stereo view of
superposition of the NTD of ScDbp5p with that of HuDbp5p-ADP.
The N-terminal extension regions with residue numbers from 71 to
100 in ScDbp5p and from 53 to 100 in HuDbp5p are shown in green
and magenta, respectively. The positions of residues 71 and 90
are also labeled.
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