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Figure 2.
A, variability profile of the three fHbp variants. Conserved
amino acids are colored in blue, conservative substitutions are
colored in gray, and variable amino acids are colored in green.
B, distribution of amino acids recognized by monoclonal
antibodies (Mabs) raised against v.1 (purple) and v.2/v.3
(green). C and D, molecular areas recognized by the bactericidal
pairs of monoclonal antibodies against v.1 (orange) and v.2
(gold) (11). E, molecular distribution of fHbp residues
recognized by monoclonal antibodies inhibiting (red), partially
inhibiting (orange), and not inhibiting (green) the fH binding
(11).
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