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Figure 2.
Figure 2. Interactions among the Motor Components during DNA
Translocation
In all three panels, gp17 N-terminal
subdomain I (N-sub I) is colored green, subdomain II (N-sub II)
yellow, and C-terminal domain cyan. (A) was generated with the
Chimera program, and (B) and (C) were generated with the CCP4mg
program (Potterton et al., 2004).
(A) A model of B-form
polyA-polyT DNA molecule is shown bound to the T4 gp17 in the
packaging mode. Potential interactions between the gp17 molecule
and the DNA are shown as dotted lines in the zoomed view.
(B) Open book view of the gp17 N- and C-terminal domain
interactions showing charge complementarity. Positively charged,
negatively charged, and hydrophobic surfaces in the contact
areas are colored blue, red, and white, respectively. Charged
residues in the contact areas are labeled. Contact areas are
defined by atoms less than 4.5 Å apart between the N- and
C-terminal domains.
(C) Stereo diagram of residues in the
N- and C-terminal domains contact areas. Oxygen and nitrogen
atoms are colored red and blue, respectively.
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