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Figure 2.
PHP β-barrel architecture. Schematic representations are
shown of canonical PHP (αβ)[7]-barrel (Left) (see Fig. S3),
the PolC PHP domain (Center), and the TaqDnaE PHP domain [Right,
based on Protein Data Bank (PDB) ID code 2HPI]. Red circles
indicate the locations of metal-chelating residues. Filled red
circles indicate the locations of metal-chelating residues that
are conserved between PolC and TaqDnaE, open circles indicate
the locations of metal-chelating residues in PolC and TaqDnaE
that are not conserved in EcoDnaE.
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