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Figure 2.
GC-1008–TGF-β3 binding interface. (A) Surface
representation of the complex. The main binding interactions of
the Fab fragments toward the TGF-β3 homodimer are accomplished
by CDR loops of the heavy chains (yellow). (B) Contact residues
of GC-1008 (gray) involved in the recognition of TGF-β3. The
TGF-β3 homodimer is shown as transparent surface representation.
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