|
Figure 2.
Fig. 2. DNA and the contacts it makes to Tgo-Pol. (a) Final
2F[obs] − F[calc] electron density map (gold) contoured at 1σ
for the primer–template region of the DNA (red) illustrating
the quality of the maps for the majority of the DNA component of
the structure. (b) Contacts observed between Tgo-Pol and DNA.
The same colour scheme as in Fig. 1 is used to identify
individual domains. Most of the contacts (dotted lines) are
polar in nature, the exception being the hydrophobic stacking
between V93 and the uracil base (continuous line). The specific
interactions with uracil are shown in more detail in Fig. 4.
|
