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Figure 2.
Fig. 2. (a) Complete interlock network between the Vav1 DH
domain, PH domain, and CRD. The DH domain is depicted in blue,
the PH domain in cyan, and the CRD in magenta. Critical
interactions between the domains are shown with dotted black
lines. (b) Superposition of the Vav1 CRD (magenta) on the Raf1
CRD (grey) previously described.^22 The overall structures are
similar, with both similarly coordinating two zinc ions depicted
as spheres.
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