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Figure 2.
Fig. 2. Subtilisin inhibition modes. Upper panel: The
subtilisin surface is shown in white, and residues in contact
with the inhibitor are shown in blue. Residues of the inhibitor
spanning subsites P4′ to P9 are shown as red sticks. Lower
panel: Zoom-in on the interaction. P5–P2′ inhibitor residues
and interacting subtilisin residues are shown as sticks;
subtilisin residues, active site residues and inhibitor residues
are shown in blue, yellow and red, respectively. β-Strands are
shown as arrows. (a) BASI (this work, chains A and C). (b) SSI
(2SIC). (c) CI-2 (2SNI). (d) OMTKY3 (1YU6, chains A and C).
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