Figure 2 - full size

 

Figure 2.
Fig. 2. A global view of the positions of the bases, the mutation of which cause anisomycin resistance in H. marismortui. The drug (gold with spherical atoms) is shown surrounded by the bases, the mutation of which leads to drug resistance (red). The backbone connecting the bases is indicated in gray. The positions occupied by the CCA end of P-site-bound tRNA (orange) and A-site-bound tRNA (green) are shown for orientation. E. coli numbering is used for all bases.

The above figure is reprinted by permission from Elsevier: J Mol Biol (2008, 379, 505-519) copyright 2008.