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Figure 2.
FIGURE 2. Structural plasticity of importin β bound to the
sIBB-(25-65) domain. a, ribbon diagram of the asymmetric unit
content of crystal form II, determined at 3.2 Å
resolution. The two complexes in the asymmetric unit have
different conformations. In complex B, on the left (in cyan),
importin β adopts an open conformation, and only the
sIBB-(40-65) helix is visible (in yellow). In complex A, on the
right (in green), importin β has a conformation identical to
crystal form I, and all residues for the sIBB-(25-65) domain are
visible (in magenta). b, superimposition of the importin β
structures from complex A (closed) and B (open) reveals
deviations up to 20 Å in the C terminus of the protein.
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