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Figure 2.
FIGURE 2. Stereoscopic overall views of (A, top; C, side)
NV RdRP·RNA·Mn^2+·NCT complex and (B, top;
D, side) uncomplexed NV RdRP (Protein Data Bank code 1SH0 (11)).
The primer (yellow) and template (magenta) strands of RNA, NCT
(red), and Mn^2+ (pink) are drawn. The C-terminal tail of
unbound NV RdRP is highlighted in red. The largest
conformational changes in the thumb and fingers domains
following the binding of RNA are highlighted with arrows.
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