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Figure 2.
Figure 2. Solution NMR structures of the apo-mSin3A PAH1
domain and the SAP25 SID–mSin3A PAH1 complex. Stereographic
views of the ensemble of 20 NMR structures of (a) the apo-mSin3A
PAH1 domain and (b) the SAP25 SID–mSin3A PAH1 complex
following a best-fit superposition of backbone atoms in
structurally ordered regions. Ribbon diagrams of the
representative structures of the respective ensembles are shown
in (c) and (d). The SAP25 SID is depicted in magenta, whereas
the mSin3A PAH1 domain is colored green. Residues 151−186 of
SAP25, although considered for the structure calculations, are
essentially unstructured and have been omitted from these views
for clarity.
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