|
Figure 2.
Figure 2. Crystal structure of the complex
ΔN25-HsCen2/P17-XPC. (a) Global view of the two
ΔN25-HsCen2/P17-XPC complexes observed in the asymmetric unit.
The centrin molecules are represented in green and orange
ribbons. The two bound P17-XPC peptides are shown in dark blue
and red ribbons. The calcium ions present in the C-terminal
binding sites of centrin molecules are represented as magenta
(site IV) and grey (site III) balls. (b) Zoom of the
centrin/peptide interaction and position of this interface
relative to the Ca^2+ binding sites. The orientation of the
complexes in (a) and (b) is the same. (c) and (d) Electron
density maps around the Ca^2+ binding sites IV (c) and III (d).
2F[o]–F[c] maps contoured at 2σ are represented.
|
